Figure 6. The Effect of Broccoli Extract on the Adenylate Cyclase Activity of v-ras-RAT1 Rat Fibroblasts. In v-ras-transformed RAT1 rat fibroblast cells, high concentration of broccoli extract suppressed the activity of adenylate cyclase on days two and nine, but induced adenylate cyclase activity on days four and six. The low concentration of the extract suppressed adenylate cyclase activity in most phases of growth, except possibly on day four.